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. 2021 May 27;11:601668. doi: 10.3389/fonc.2021.601668

Table 1.

Study on the correlation between the total number of CTCs and the clinical characteristics of HCC.

Clinical characteristics CTC≤13.3 CTC>13.3 P
Sex (Male/Female) 97/16 44/3 0.166
Age (≤60/>60 years) 86/27 37/10 0.721
Tumor Size (≤5/>5 cm) 76/37 21/26 0.008
Tumor Number (1/>1) 90/23 32/15 0.118
Differentiation (H/M/L) 20/69/24 3/34/10 0.164
BCLC Stage (A/B+C) 72/41 21/26 0.026
Metastasis (Yes/No) 14/99 7/40 0.669
AFP (≤400/>400 μg/L) 72/41 32/15 0.598
PIVKA (≤400/>400 μg/L) 69/44 21/26 0.057
Vascular Invasion (+/-) 36/77 23/24 0.041
MVI (Yes/No) 29/84 20/27 0.035
MVD (Yes/No) 19/94 9/38 0.723
HBsAg (+/-) 101/12 42/5 0.997
Direct Bilirubin (≤4/>4) 53/60 17/30 0.213
Total Bilirubin (≤10/>10) 12/101 1/46 0.073
ALT (≤84/>84 IU/L) 98/15 36/11 0.114
TNM (I-II/III-IV) 82/31 31/16 0.403
Edmondson stage (H/M/L) 20/69/24 3/34/10 0.164
HBV DNA (≤100/>100) 71/42 18/29 0.004
NLR (≤1.77/>1.77) 26/87 12/35 0.733
INR (≤1/>1) 42/71 15/32 0.527
APRI (≤1/>1) 102/11 42/5 0.862
HB (≤120/>120) 13/100 4/43 0.576
Neutrophil (≤4/>4) 85/28 30/17 0.144
Lymphocyte (≤1/>1) 35/78 9/38 0.127
PT (≤12/>12) 63/50 23/24 0.431
PLT (≤100/>100) 32/81 13/34 0.933
AST (≤45/>45) 72/41 22/25 0.048
ALB (≤35/>35) 9/104 5/42 0.586
ICG (≤10/>10%) 96/17 40/7 0.9811

P value < 0.05 is Statistically Highly Significant (Pearson Correlation Coefficient); INR, International Normalized Ratio; APRI, AST to platelet ratio index; HB, hemoglobin; PT, prothrombin time; PLT, platelets; AST, glutamic oxaloacetic transaminase; ALB, albumin; ICG, indocyanine green. Bold font is used to describe p<0.05, which is statistically significant.