Table 3.

Cox proportional regression analysis of univariate and multivariate.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	P	HR (95% CI)	P
Sex (Male/Female)	1.6(0.845-3.033)	0.149
Age (≤60/>60 years)	0.977(0.594-1.607)	0.926
Tumor Size (≤5/>5 cm)	1.557(1.002-2.417)	0.049	.
Tumor Number (≤1/>1)	1.613(0.984-2.644)	0.058	.
Differentiation (H/M/L)	1.466(0.704-3.053)	0.307
BCLC Stage (A/B+C)	1.657(1.067-2.572)	0.024	.
Metastasis (Yes/No)	1.892(0.958-3.737)	0.066
AFP (≤400/>400 μg/L)	2.042(1.303-3.199)	0.002	2.733(1.667-4.481)	0.000067
PIVKA (≤400/>400 μg/L)	1.593(1.023-2.481)	0.039
E CTC (+/-)	1.295(0.827-2.026)	0.258		.
Mixed CTC (+/-)	1.068(0.577-1.976)	0.835
M CTC (+/-)	1.182(0.764-1.83)	0.452
CTC (+/-)	1.233(0.567-2.680)	0.597
CTC (≤13.3/>13.3)	1.039(0.648-1.668)	0.872		.
Nanog (≤6.7/>6.7)	1.881(1.215-2.911)	0.005	2.33(1.476-3.679)	0.000282
Vascular thrombus (+/-)	0.913(0.577-1.445)	0.697
MVI (Yes/No)	0.795(0.49-1.292)	0.355	0.542(0.311-0.943)	0.03
MVD (Yes/No)	1.711(0.998-2.932)	0.051	2.418(1.331-4.392)	0.004
HBsAg (+/-)	1.816(0.835-3.953)	0.132		.
Direct Bilirubin (≤4/>4)	0.873(0.562-1.356)	0.546	.	.
Total bilirubin (≤10/>10)	0.747(0.342-1.722)	0.493	.
ALT (≤84/>84 IU/L)	0.866(0.469-1.6)	0.647
TNM (I-II/III-IV)	1.318(0.826-2.106)	0.247		.
Edmondson (I-II/III-IV)	1.498(0.945-2.376)	0.086
HBV DNA (100≤/>100)	1.711(1.099-2.662)	0.017		.
NLR (≤1.77/>1.77)	0.74(0.446-1.23)	0.245	.	.
INR (≤1/>1)	0.966(0.593-1.574)	0.89
APRI (≤1/>1)	0.638(0.293-1.389)	0.257	0.382(0.169-0.863)	0.021
HB (≤120/>120)	1.43(0.685-2.984)	0.341		.
Neutrophil (≤4/>4)	0.921(0.555-1.528)	0.75	0.543(0.298-0.991)	0.047
Lymphocyte (≤1/>1)	1.224(0.757-1.979)	0.409
PT (≤12/>12)	0.938(0.604-1.456)	0.774	.
PLT (≤100/>100)	1.308(0.809-2.116)	0.274
AST (≤45/>45)	1.132(0.715-1.791)	0.597	.
ALB (≤35/>35)	0.734(0.367-1.469)	0.382	.
ICG (≤10/>10%)	1.058(0.584-1.916)	0.852

Bold font is used to describe p<0.05, which is statistically significant.