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. 2021 May 27;12:684344. doi: 10.3389/fimmu.2021.684344

Figure 8.

Figure 8

Sorafenib suppresses Aβ-mediated astrogliosis in 5xFAD mice. (A) Scheme for the treatment of 5xFAD mice with sorafenib. (B, D) Immunofluorescence staining with anti-Iba-1 and anti-GFAP antibodies of brain slices from 5xFAD mice treated as described in (A). (C, E) Quantification of the data in (B, D) (analyzed number of brain slices/images (n); Vehicle: =21, Sorafenib: n= 18). **p < 0.01. Scale bar = 200 μM.