Skip to main content
letter
. 2021 May 18;5(3):290–301. doi: 10.1002/evl3.226

Table 1.

List of parameters, with their dimensions, the value used in the main text, ranges explored in Supporting Information Section 1, and the effect on evolutionary outcome

Parameter Definition Dimensions Main text value (SI range) Bistability when
λ
Replication rate Time−1 1 (0.5, 2) High
γ
Death rate Volume cells−1 time−1 1 (0.5, 2) Low
A
Antibiotic‐associated death rate Time−1 1 (0, 2) Low
cR
Cost of antibiotic resistance Dimensionless 0.05 (0, 0.5) High
cP
Cost of plasmid carriage Dimensionless 0.075 (0, 0.5) Low
β
Plasmid transmission rate Volume cells−1 time−1 0.2 (0, 0.25) High
s
Segregation loss Dimensionless 0.005 (0, 0.1) Low

Note: More specifically, the fifth column indicates whether the region of bistability (where resistance can be either plasmid‐borne or chromosomal) occurs at high or low parameter values compared to the region where only chromosomal resistance is evolutionarily stable (see Supporting Information Section 1). The parameter units are arbitrary. The main text values are chosen to best illustrate the range of evolutionary stable outcomes.