Figure 3.

Schematic representation of metabolic pathways. Glycolysis requires the three rate-limiting enzymes shown in the green ovals. Gluconeogenesis needs the four key enzymes shown in the red ovals. Glyceroneogenesis is a truncated version of gluconeogenesis sharing the same enzymes. Abbreviations: 3-PG, 3-phosphoglycerate; DHAP, dihydroxyacetone phosphate; F-1,6-P, fructose-1,6-biphosphate; F-6-P, fructose-6-phosphate; FBP, fructose-1,6-bisphosphatase; FFA, free fatty acid; G-3-P, glyceraldehyde-3-phosphate; G-6-P, glucose-6-phosphate; G6PC, glucose-6-phosphatase; HK, hexokinase; MDH, malate dehydrogenase; OAA, oxaloacetate; PC, pyruvate carboxylase; PCK, phosphoenolpyruvate carboxykinase; PEP, phosphoenolpyruvate; PFK, phosphofructokinase; PK, pyruvate kinase; R-5-P, ribose-5-phosphate; TG, triglyceride.