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. 2021 May 27;12:653088. doi: 10.3389/fimmu.2021.653088

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Copyright © 2021 Li, Frei, Labrada, Rong, Liang, Samojlik, Sun, Barash, Keselowsky, Bayer and Stabler

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytocompatibility of TGF-β1 PLGA Microparticles with Rat Pancreatic Islets. Representative LIVE/DEAD images of (A) control islets, (B) islets incubated with TGF-β1 PLGA microparticles, and (C) islets incubated with soluble TGF-β1. Red = dead cells (EthD-1), Green = viable cells (Calcein AM). Scale bars = 50 µm. (D) MTT metabolic assay, n=3. (E) Stimulation index resulted from glucose stimulated insulin response, High/Low 1, n=3. Paired Tukey’s test was conducted for mean comparison, with n.s., not significant.