Phylogenetic analysis of the RAP domain in Eukaryota. The maximum-likelihood tree is built from an alignment of RAP domains extracted from 267 proteins corresponding to 19 different species. Alveolates are represented by Aconoidasida (Plasmodium falciparum, Plasmodium vivax, Plasmodium berghei and Theileria annulata) in red, Conoidasida (Toxoplasma gondii and E. tenella) in brown, Chromerida (V. brassicaformis and Chromera velia) in blue, and Perkinsus marinus and Symbiodinium microadriaticum in purple. Viridiplantae are represented by Chlorophyta (G. pectorale, Monoraphidium neglectum and Ostreococcus tauri) in green, and Streptophyta (A. thaliana, Oryza sativa and Citrus sinensis) in pale green. Opisthokonta (H. sapiens, Danio rerio and Drosophila melanogaster) are indicated in grey. The green arc indicates the clade enriched in RAP proteins of Chlorophyta species. Bootstrap values (>50 %) are shown on respective branches. The scale indicates the number of substitutions per site.