Fig. 5.

The C-terminal extension of the CsdA-like helicases contains a DbpA RNA binding domain. (a) A schematic showing the Pfam domains present in the CsdA-like helicases: the DEAD/DEAH box helicase domain (DEAD, PF00270), the helicase conserved C-terminal domain (helicase C, PF00271) and the DbpA RNA binding domain (DbpA, PF03880). (b) Alignments generated with muscle of the C-terminal extensions of selected CsdA-like helicases. The final conserved DEAD-box helicase motif, HRIGRXXR, is marked with a grey background on the alignment. The conserved DbpA RNA binding domain is indicated in bold, with amino acids coloured based on their chemical properties. Note that this domain is not present in members of the CrhR-like clade.