TABLE 2.
Patient Characteristics Separated by Those Patients Who Achieved Objective Response and No Objective Response on Treatment With Pembrolizumab
Patient ID | No Objective Response | Objective Response | ||
---|---|---|---|---|
Mean | Mean | |||
Clinical characteristics | ||||
Age (years) | 42 | 50 | ||
Gender F/M | ||||
Ethnicity | ||||
Overall survival (months) | 7 | 14 | ||
Status Alive/Dead | ||||
Stage | ||||
AJCC classification | M1c: 2 | M1a: 1, M1c: 2 | ||
LDH UI/L | 404 | 181 | ||
Treatment | ||||
Drug | Pembrolizumab: 2 | Pembrolizumab: 3 | ||
Baseline FLT-PET | ||||
Uptake | ||||
SUV max | 6.8 | 7.8 | ||
SUV peak | 5.7 | 6.1 | ||
SUV mean | 4 | 3.6 | ||
SUV SD | 0.8 | 0.8 | ||
Tumor Burden | ||||
TLP | 351.1 | 115.1 | ||
PTV | 97.4 | 30.8 | ||
SLR | 0.6 | 0.4 | ||
BLR | 0.9 | 1.3 | ||
FLT-PET at 6 weeks | ||||
Uptake | ||||
Delta-SUV max | 1.1 | −0.5 | ||
Delta-SUV peak | 1.4 | −0.5 | ||
Delta-SUV mean | 0.9 | −0.4 | ||
Delta-SD | −0.1 | −0.6 | ||
Tumor Burden | ||||
Delta-TLP | 44.2 | −0.7 | ||
Delta-PTV | 14.6 | −0.6 | ||
Delta-SLR | −0.1 | 0.1 | ||
Delta-BLR | 0.2 | 0.1 |