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. 2021 Jun 10;31(8):847–860. doi: 10.1038/s41422-021-00519-4

Table 3.

In vivo toxicity of BE-33.

Administration Species Dosage (mg/kg) Number of animals Frequency Results
Tail vein injection C57BL/6 5/10/50 5/group Repeat dose No significant changes in body weight were observed with up to 50 mg/kg of BE-33 compared with the control group, however, in the 50 mg/kg administration group, a pronounced decrease in locomotor activity was observed.