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. 2021 Jun 2;22(2):580. doi: 10.3892/ol.2021.12841

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Low miR-497 expression in TNBC is associated with poor survival. (A) Expression of miR-497 in 36 samples from patients with TNBC tissues and matched non-cancerous breast tissue samples. (B) Expression of miR-497 in breast cancer cell lines and MCF-10A cells. The data are normalized to the MCF-10A group. (C and D) Expression of miR-497 in patients with TNBC with (C) advanced stage or (D) different N stages. (E) Association of high or low expression of miR-497 with overall survival in patients with TNBC patients. (F) miR-497 expression is upregulated in MDA-MB-231 and MDA-MB-468 cells following transfection with miR-497 mimics. *P<0.05, **P<0.01, ***P<0.001. TNBC, triple-negative breast cancer; miR, microRNA; N, lymph node metastasis; NC, negative control.