TABLE 1.

Circadian associated DNA binding factors and corresponding binding sequences

Binding site	Description	DNA binding sequence
E-box	E-boxes are CLOCK:BMAL1 binding sites central to molecular circadian clock function (Buhr & Takahashi, 2013; Lowrey & Takahashi, 2011).	5′-CACGTG-3′ 5′-CACGTT-3′ (Lowrey & Takahashi, 2011)
D-box	D-boxes are binding sites for DBP, a transcription which oscillates with the circadian clock (Ueda et al., 2005)	5′-TTAYGTAA-3′ (Ueda et al., 2005)
RORE element	RORE elements are Rev-erbα binding sites (Harding & Lazar, 1993)	5′-RGGTCA-3′ (Harding & Lazar, 1993).
CRE element	Cyclic AMP response elements are binding sites for cAMP, which is commonly associated with the circadian clock (Carlezon, Duman, & Nestler, 2005)	5′-TGACGTCA-3′ (Carlezon et al., 2005)