Table 2.
Comparison of clinical features and pregnancy outcomes between HDP-related and non-HDP Pr-AKI patients
| Variables | HDP-related N = 48 (50 fetuses) |
Non-HDP N = 50 (50 fetuses) |
P value |
|---|---|---|---|
| Age (years) | 28.3 ± 5.1 | 26.9 ± 6.0 | 0.255 |
| SBP (mmHg) | 154.3 ± 19.0 | 110.6 ± 13.5 | < 0.001 |
| DBP (mmHg) | 101.4 ± 15.3 | 69.3 ± 10.1 | < 0.001 |
| Serum ALB (g/L) | 24.9 ± 5.6 | 27.5 ± 5.3 | 0.020 |
| SCr (umol/L) | 86(77–98) | 90(78–111) | 0.355a |
| Serum UA (umol/L) | 477.1 ± 82.8 | 406.2 ± 115.7 | 0.001 |
| Maternal death (n%) | 2(4.0 %) | 2(3.7 %) | 1.000b |
|
Gestational age at delivery (in weeks) |
37.1 ± 2.8 | 37.0 ± 4.0 | 0.858 |
| Delivery via cesarean section (n%) | 27(56.3 %) | 15(31.3 %) | 0.014 |
| Pre-term birth (n%) | 17(35.4 %) | 12(26.1 %) | 0.328 |
| Stillbirth/neonatal death (n%) | 6(13.6 %) | 10(21.3 %) | 0.339 |
| Neonatal weight (g) | 2770.2 ± 647.4 | 3023.8 ± 523.7 | 0.054 |
| Apgar score at 1 min | 7.8 ± 3.3 | 7.7 ± 3.7 | 0.923 |
| IUGR (n%) | 11(25.0 %) | 1(2.3 %) | 0.003b |
| Admission to NICU (n%) | 11(22.0 %) | 3(6.5 %) | 0.019b |
| LBWI (n%) | 17(37.8 %) | 7(15.9 %) | 0.020 |
| Renal recovery on discharge (n%) | 29(76.3 %) | 35(85.4 %) | 0.305 |
AKI acute kidney injury; HDP hypertensive disorders of pregnancy; SBP systolic blood pressure; DBP diastolic blood pressure; ALB albumin; SCr serum creatinine; UA uric acid; IUGR intrauterine growth restriction; LBWI low birth weight infant; NICU neonatal intensive care unit
Values for categorical variables were given as number (percentage); values for continuous variables were given as mean ± standard deviation or median (interquartile range)
P < 0.05 was considered to be statistically significant
a: Wilcoxon 2-sample tests
b: Fisher exact test