Effect of desflurane on mutual information between neurons recorded in primary and secondary visual cortex (V1, V2), cortical layers 3 and 5 (L3, L5), and their subregions. Anesthetic states 1 to 9 correspond to consecutive desflurane concentrations of 0, 2, 4, 6, 8, 6, 4, 2, 0 percent, respectively. Mutual information is in relative units, plotted as mean and 95% confidence interval. *: statistically significant quadratic trend with consecutive anesthetic states.