Hur 2012.
Study characteristics | ||
Methods | RCT, 2 arms, 59 randomised Setting: South Korea, Maria Fertility Hospital, one centre Recruitment period: no description |
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Participants |
Criteria related to previous IVF failure: yes, first IVF cycle only Inclusion criteria: all patients were under 35 years old, day 3 follicle‐stimulating hormone level were below 10 IU/L. Exclusion criteria: infertility cause of uterine factor, severe male factor, and severe endometriosis were excluded. |
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Interventions |
Study group: endometrial biopsy was done with a biopsy catheter (pipelle de cornier, France), performed only one time on starting day of stimulation. Control group: no procedure |
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Outcomes | Reported in paper: clinical pregnancy Obtained by author correspondence: ‐ |
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Notes | Trial registration: authors confirmed trial was not registered Additional concerns and comments: none Funding: no description Author correspondence: yes, correspondence undertaken with Dr Yeonhee Ka (miriuh@daum.net) and Dr Hur (cyhur68@gmail.com). Authors provided the poster that was presented at the conference. Publication: abstract only (and poster) |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Authors confirmed quote:"patient allocation was made by computerized randomization" |
Allocation concealment (selection bias) | Unclear risk | No description |
Blinding of participants and personnel (performance bias) All outcomes | High risk | No blinding was implemented |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Only reported objective outcomes |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Only abstract available therefore difficult to assess level of attrition |
Selective reporting (reporting bias) | High risk | Trial was not registered and important outcomes such as live birth and adverse events not reported |
Other bias | High risk | Trial published as abstract only with limited detail, and further information not obtained from author correspondence. Trial not registered. |