Zygula 2016.
| Study characteristics | ||
| Methods | RCT, 2 arms, 120 randomised Setting: Warsaw Medical University Poland ‐ one centre Recruitment period: not stated |
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| Participants |
Criteria related to previous IVF failure: yes, previous IVF failure (not defined) Inclusion criteria: <40 years old Exclusion criteria: ‐ |
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| Interventions | Study group: endometrial biopsy 7 days after ovulation in the cycle before the IVF cycle Control group: casual care | |
| Outcomes | Reported in paper: Clinical pregnancy Obtained by author correspondence: ‐ |
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| Notes | Trial registration: unclear Additional concerns and comments: none Funding: not stated Author correspondence: attempted but unsuccessful Publication: abstract only |
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| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Stated as "randomised" only |
| Allocation concealment (selection bias) | Unclear risk | No description |
| Blinding of participants and personnel (performance bias) All outcomes | High risk | No blinding employed |
| Blinding of outcome assessment (detection bias) All outcomes | Low risk | Only objective outcomes reported |
| Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Level of attrition is unclear |
| Selective reporting (reporting bias) | High risk | Study does not appear to be registered and important outcomes such as live birth and adverse events not reported |
| Other bias | High risk | Trial published as abstract only with limited detail, and further information not obtained from author correspondence. Trial not registered. |
ART: assisted reproductive technology; BMI: body mass index; ESHRE: European Society of Human Reproduction and Embryology; FET: frozen embryo transfer; FIGO: International Federation of Gynecology and Obstetrics; HSG: hysterosalpingography; ICSI: intracytoplasmic sperm injection; ITT: intention‐to‐treat; IU: international unit; IVF: in vitro fertilisation; RCT: randomised controlled trial; RIF: recurrent implantation failure; SD: standard deviation; SNOSE: sequentially numbered, opaque sealed envelopes; USTV: ultrasonic transvaginal.