ISRCTN63112626.
Study name | Effect of endometrial injury on repeat implantation failure following in vitro fertilisation embryo transfer or frozen embryo transfer: a randomised controlled study |
Methods | RCT |
Participants |
Inclusion criteria: patients with repeated implantation failure (3 or more) undergoing in vitro fertilisation embryo transfer (IVF‐ET) or frozen embryo transfer (FET); patients with normal preoperative routine checks; patients ≤ 40 years of age with basal follicle‐stimulating hormone (FSH) < 10 IU/L and > 5 follicles in bilateral ovaries; patients without history of uterine cavity operation within 2 months Exclusion criteria: patients with hydrosalpinx; patients with history of endometrial adhesion; patients with uterine malformation; patients with acute genital tract inflammation; patients with history of using hormone such as oral contraceptive within 3 months |
Interventions |
Intervention: endometrial scratching on fifth day after ovulation before IVF or FET cycle in study group. No extra administration before IVF or FET cycle in control group Control: no intervention |
Outcomes | Clinical pregnancy |
Starting date | November 2011 |
Contact information | Prof. Caihong Ma: no contact details provided |
Notes | Trial registration status on3 July 2020. No longer recruiting Investigator emailed multiple times, however have not received any reply from the researchers and could not locate any publication |