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. 2021 Jun 10;2021(6):CD009517. doi: 10.1002/14651858.CD009517.pub4

ISRCTN63112626.

Study name Effect of endometrial injury on repeat implantation failure following in vitro fertilisation embryo transfer or frozen embryo transfer: a randomised controlled study
Methods RCT
Participants Inclusion criteria: patients with repeated implantation failure (3 or more) undergoing in vitro fertilisation embryo transfer (IVF‐ET) or frozen embryo transfer (FET); patients with normal preoperative routine checks; patients ≤ 40 years of age with basal follicle‐stimulating hormone (FSH) < 10 IU/L and > 5 follicles in bilateral ovaries; patients without history of uterine cavity operation within 2 months
Exclusion criteria: patients with hydrosalpinx; patients with history of endometrial adhesion; patients with uterine malformation; patients with acute genital tract inflammation; patients with history of using hormone such as oral contraceptive within 3 months
Interventions Intervention: endometrial scratching on fifth day after ovulation before IVF or FET cycle in study group. No extra administration before IVF or FET cycle in control group
Control: no intervention
Outcomes Clinical pregnancy
Starting date November 2011
Contact information Prof. Caihong Ma: no contact details provided
Notes Trial registration status on3 July 2020. No longer recruiting
Investigator emailed multiple times, however have not received any reply from the researchers and could not locate any publication