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TEM revealed detrusor mitochondrial changes A normal mitochondria (grade 0). B–C. Loss and dissolution of the mitochondrial cristae in one (grade 1) or multiple mitochondrion area(s) (grade 2). D Mitochondrial swelling and progressive dissolution of the mitochondrial cristae (grade 3), E–F Complete loss and dissolution of the mitochondrial cristae and destruction of the inner mitochondrial membrane (grade 4) and the outer mitochondrial membrane rupture (grade 5). Reduced from ×400000
