Fig. 7.

Muscularis lesions A and G, control group. B–C and H, OD group. D–F and I, DM group. A, B and D showed mitochondria at the same magnification. B–C, degenerating muscle cells with uneven thickness or focally disrupted sarcolemma, disrupted sarcoplasmic myofilaments and vacuolar degeneration, and cell junctions reduced with depleted caveolae. D predominant mitochondrial vacuolar degeneration. E Flocculent degeneration was seen in the sarcoplasm and axoplasm in which cytoplasm was replaced by amorphous particulate material. F Detrusor profile linked by protrusion junctions with moderately widened intercellular spaces, scarce intermediate muscle cell junctions. Note the distinctive nucleus coming into another cell. G–I Neuroeffector junction with muscle cells. H. Mitochondrial vacuolar degeneration in the axoplasm. I Axolemmas are fuzzy, breached, disrupted residual silhouettes of synaptic vesicles, and mitochondrial vacuolar degeneration