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. 2021 Jun 8;19(2):15593258211016237. doi: 10.1177/15593258211016237

Figure 1.

Figure 1.

Exposure to low doses of irradiation decreases Ly6CHi pro-inflammatory circulating monocytes but does not affect anti-inflammatory Ly6C Lo cells. ApoE-/- mice were exposed to low doses of y ionizing radiation at dose-rates of 1.4 and 50 mGy.h-1. Mice were sacrificed at day 12-50 post-irradiation and blood monocytes analyzed by flow cytometry. No effects of irradiation were noted in Ly6C Lo cells. However, proportions of Ly6CHI monocytes (among CD11b+Gr1- populations) were reduced at all doses of irradiation, most consistently in mice exposed to the dose-rate of 50 mGy.h-1. Data are mean ± SEM of n = 5-8. *P < 0.05, **P < 0.01 vs non-irradiated, age-matched control.