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. Author manuscript; available in PMC: 2021 Jun 10.
Published in final edited form as: Curr Protoc Hum Genet. 2020 Jun;106(1):e101. doi: 10.1002/cphg.101

Table 5.

Tools to Investigate Differentially Accessible Regions

Languages Notes Docs Citation
DAStk Python Identifies changes in transcription factor activity by looking at changes in chromatin accessibility +++ Tripodi et al. (2018)
Last updated: 2020
diffTF Python; R Identifies differential transcription factors. Can operate in basic mode with just chromatin accessibility or in classification mode where it integrates RNA-seq. +++ Berest et al. (2019)
Last updated: 2020