Table 1.
Demographic characteristics of infants with T13 or T18 in 3 treatment groups (n = 467).
| Entire cohort | Surgical treatment | Intensive medical treatment | Non-intensive treatment | p-value | |
|---|---|---|---|---|---|
| 467 | 129 | 292 | 46 | ||
| Gestational age at birth (weeks) | n(%) | n(%) | n(%) | n(%) | 0.009 |
| ≤27 + 6/7 | 5 (1%) | 2 (2%) | 3 (1%) | 0(0%) | |
| 28 to 31 + 6/7 | 41 (9%) | 7 (5%) | 32 (11%) | 2 (4%) | |
| 32 to 36 + 6/7 | 154 (33%) | 53 (41%) | 94 (32%) | 7 (15%) | |
| ≥37 | 267 (57%) | 67 (52%) | 163 (56%) | 37 (81%) | |
| Age at admission (days) median (IQR) | 1 [0, 4] | 1 [0, 22] | 0 [0, 2] | 1 [0, 14] | <0.001 |
| Birth weight (g) | |||||
| < = 1500 g | 100 (22%) | 25 (20%) | 69 (24%) | 6 (13%) | 0.127 |
| 1501–2499 g | 259 (56%) | 81 (64%) | 150 (52%) | 28 (62%) | |
| > = 2500 g | 101 (22%) | 21 (16%) | 69 (24%) | 11 (25%) | |
| Small-for-gestational age | 305 (65%) | 91 (70%) | 180 (62%) | 34 (74%) | 0.091 |
| Male gender | 190 (41%) | 52 (40%) | 123 (42%) | 15 (33%) | 0.472 |
| Maternal racea | |||||
| White | 241 (52%) | 67 (52%) | 152 (52%) | 22 (48%) | 0.244 |
| Black | 119 (25%) | 35 (27%) | 73 (25%) | 11 (24%) | |
| Other | 65 (14%) | 17 (13%) | 41 (14%) | 7 (15%) | |
| Asian | 10 (2%) | 1 (1%) | 9 (3%) | 0(0%) | |
| Hawaiian/Pacific Islander | 4 (1%) | 0(0%) | 2 (1%) | 2 (4%) | |
| Inborn | 58 (12%) | 11 (8%) | 38(13%) | 9 (19%) | 0.036 |
| Delivery type | |||||
| Cesarean | 278 (60%) | 80 (62%) | 182 (62%) | 16 (35%) | <0.001 |
| Vaginal | 175 (37%) | 44 (34%) | 106 (36%) | 25 (54%) | |
| Unknown | 14 (3%) | 5 (4%) | 4 (2%) | 5 (11%) | |
| 1-minute APGAR score | |||||
| < = 2 | 130 (30%) | 38 (31%) | 88 (31%) | 4 (11%) | <0.001 |
| 3 to 6 | 214 (49%) | 59 (49%) | 143 (51%) | 12 (33%) | |
| > = 7 | 92 (21%) | 24 (20%) | 48 (18%) | 20 (56%) | |
| 5-minute APGAR score | |||||
| < = 2 | 23 (5%) | 5 (4%) | 16 (6%) | 2 (6%) | 0.059 |
| 3 to 6 | 143 (33%) | 41 (34%) | 98 (35%) | 4 (11%) | |
| > = 7 | 270 (62%) | 75 (62%) | 165 (59%) | 30 (83%) | |
| Prenatal diagnosis | 171 (37%) | 55 (43%) | 98 (33%) | 18 (39%) | 0.191 |
| Proportion of prenatally diagnosed cases who were inborn | 41 (24%) | 9 (16%) | 25 (25%) | 7 (39%) | 0.131 |
| Primary reason for admission | |||||
| Anomalies or syndrome | 190 (41%) | 32 (25%) | 136 (47%) | 22 (48%) | <0.001 |
| Respiratory | 87 (19%) | 56 (43%) | 29 (10%) | 2 (4%) | <0.001 |
| Cardiac | 81 (17%) | 14 (11%) | 57 (20%) | 10 (22%) | 0.068 |
| Preterm birth | 60 (13%) | 11 (8%) | 45 (15%) | 4 (9%) | 0.102 |
| Surgical evaluation | 34 (7%) | 11 (8%) | 15 (5%) | 8 (17%) | 0.010 |
IQR interquartile range.
Percentages are column percentages.
p values of <0.05 are in bold font.
aContain missing values and numbers do not add up to 100%.