Table 2.
Hospital Outcomes for Infants with T13 or T18 who received surgical, intensive medical or non-intensive treatment (n = 467).
| Entire Cohort | Surgical treatment | Intensive medical treatment | Non-intensive treatment | p-value | |
|---|---|---|---|---|---|
| 467 | 129 | 292 | 46 | ||
| Died before hospital discharge | 231 (49) | 42 (32) | 179 (61) | 10 (22) | <0.001 |
| Of those who died, | |||||
| DNR Orders | 175 (76) | 32 (76) | 133 (74) | 10 (100) | 0.182 |
| Medical care withdrawn | 164 (71) | 34 (81) | 129 (72) | 1 (10) | <0.001 |
| LOS, median (IQR) | 7 [3,17] | 17 [9,47] | 7 [3,15] | 2 [0, 3] | <0.001 |
| Survived to hospital discharge | 188 (40) | 66 (51) | 89 (30) | 33 (72) | <0.001 |
| Of those who survived to discharge, | |||||
| LOS, median (IQR) | 13 [6,25] | 27 [16,43] | 10 [6,17] | 6 [3,12] | <0.001 |
| Total ventilator days, median (IQR) | 5 [2,10] | 6 [4,18] | 3 [1,5] | . [.,.] | 0.003 |
| Therapy at discharge | |||||
| Feeding support | |||||
| Gastrostomy tube feedings | 41 (22) | 41 (62) | 0(0) | 0(0) | <0.001 |
| Respiratory support at discharge | |||||
| Tracheostomy | 5 (3) | 5 (8) | 0(0) | 0(0) | 0.009 |
| Apnea monitor | 66 (35) | 28 (42) | 31 (35) | 7 (21) | 0.241 |
| Home oxygen | 92 (49) | 34 (51) | 51 (57) | 7 (21) | 0.002 |
| Mechanical ventilator | 5 (3) | 4 (6) | 1 (1) | 0(0) | 0.097 |
| Route of feeds at discharge | |||||
| Breast | 20 (11) | 3 (4) | 9 (10) | 8 (24) | 0.026 |
| Bottle | 51 (27) | 10 (15) | 25 (28) | 16 (48) | 0.005 |
| Tube feedings | 157 (83) | 62 (94) | 75 (84) | 20 (61) | 0.001 |
| Gastrostomy tube feedings | 41 (22) | 41 (66) | 0(0) | 0(0) | |
| Nasogastric/orogastric tube feedings | 113 (60) | 18 (27) | 75 (84) | 19(58) | |
| Transpyloric feeds | 3(1) | 2(3) | 0(0) | 1(3) | |
| Discharged with a referral to palliative carea | 97/177(55%) | 22/64(34%) | 54/83(65%) | 21/30(70%) | <0.001 |
| Transferred outb | 48 (10) | 21 (16) | 24 (8) | 3 (6) | 0.029 |
| LOS median (IQR) | 17 [6,35] | 35 [19,68] | 8 [2,19] | 2 [0, 7] | <0.001 |
| Of those who transferred out, reasons for transfer, | |||||
| Chronic care | 1 (2) | 1 (5) | 0(0) | 0(0) | 0.041 |
| Growth/discharge planning/continuing care | 17 (35) | 7 (33) | 8 (33) | 2 (67) | |
| Medical/diagnostic services | 1 (2) | 1 (5) | 0(0) | 0(0) | |
| Palliative care | 18 (37) | 3 (14) | 14 (58) | 1 (33) | |
| Surgery | 10 (21) | 9 (43) | 1 (4) | 0(0) | |
| Unknown | 1 (2) | 0(0) | 1 (4) | 0(0) | |
DNR do not resuscitate, IQR interquartile range, LOS length of stay.
p values of <0.05 are in bold font.
aContains 11 missing values.
bThe number of infants transferred out (n = 48) is included in the denominator for percentages.