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. 2021 May 27;11:650963. doi: 10.3389/fonc.2021.650963

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Copyright © 2021 Chai, Zhang, Ao, Zhu, Wu, Lau, Sun and Cheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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AXL overexpression in TECs but not tumor cells indicates poor prognosis. (A) Low expression of AXL in TECs was associated with prolonged survival (OS: p = 0.009; DFS: p = 0.013). (B) AXL overexpression in tumor cells indicated no significant association with poor prognosis. (C) AXL expressed in TECs was associated with lower OS compared with AXL expressed in TCs. (D) High expression of AXL in TECs indicated poorer survival compared with high expression of AXL in TCs (OS: p = 0.033; DFS: p =0.650). (E) There was no significant difference in survival between patients with low expression of AXL in TECs and patients with low expression of AXL in TCs (OS: p = 0.431; DFS: p =0.574).