Skip to main content
. 2021 May 27;12:654869. doi: 10.3389/fgene.2021.654869

TABLE 1.

Primary information on the PDGFRA rs6554163 T > A, RASGRF1 rs6495367 G > A, PTPN5 rs1550870 C > T, PTPRR rs11178469 T > C polymorphisms.

Control group vs. incident myopia group
Control group vs. significant myopic shift group
Gene SNP MAFa for the Chinese populationb Call rate (%) MAFa in our controls (n = 174) P-value for the HWEc test in our controls MAFa in our controls (n = 281) P-value for the HWEc test in our controls P-value in GWAS
PDGFRA rs6554163 T > A 0.221 99.10 0.21 0.259 0.20 0.266 2.8 × 10–6 (Guggenheim et al., 2013)
RASGRF1 rs6495367 G > A 0.490 98.58 0.49 0.546 0.48 0.340 1.95 × 10–24 (Tedja et al., 2018)
PTPN5 rs1550870 C > T 0.296 98.82 0.27 0.570 0.27 0.176 9.9 × 10–13 (Pickrell et al., 2016)
PTPRR rs11178469 T > C 0.394 99.13 0.41 1 0.41 0.622 1.33 × 10–13 (Tedja et al., 2018)

aMinor allele frequency. bRefer to https://www.internationalgenome.org/category/dbsnp. cHardy-Weinberg equilibrium.