TABLE 7.
GMDR results of SNP-SNP interactions related to incident myopia.
Model | Training balanced accuracy | Testing balanced accuracy | Cross-validation consistency | Sign test (p)a |
PTPN5 rs1550870 | 0.5820 | 0.5751 | 10/10 | 9 (0.0107) |
PTPN5 rs1550870, PTPRR rs11178469 | 0.5871 | 0.5047 | 6/10 | 6 (0.3770) |
RASGRF1 rs6495367, PTPRR rs11178469, PDGFRA rs6554163 | 0.6183 | 0.4598 | 4/10 | 3 (0.9453) |
aAdjusted for sex, age, near-work time, outdoor time, and baseline SE. The bold values are P < 0.05.