TABLE 8.
GMDR results of SNP-SNP interactions related to significant myopic shift.
Model | Training balanced accuracy | Testing balanced accuracy | Cross-validation consistency | Sign test (p)a |
RASGRF1 rs6495367 | 0.5643 | 0.5324 | 7/10 | 7 (0.1719) |
PTPRR rs11178469, PDGFRA rs6554163 | 0.5856 | 0.5346 | 6/10 | 9 (0.0107) |
RASGRF1 rs6495367, PTPN5 rs1550870, PTPRR rs11178469 | 0.6144 | 0.5049 | 5/10 | 6 (0.3770) |
aAdjusted for sex, age, near-work time, outdoor time, and baseline SE. The bold values are P < 0.05.