TABLE 4.

Moderation of blood loss outcomes by latent class with AMTSL among 2322 hospital vaginal births attended by nurse-midwives in the United States, 2012-2017

	Class	Total blood loss coefficient (95% CI)	≥500 mL PPH OR (95% CI)	≥1000 mL PPH OR (95% CI)	Blood transfusion OR (95% CI)
Main effects	Physiologic: A	Reference	Reference	Reference	Reference
Class	Dysfunctional: B	70.38 (29.41-111.16)**	1.88 (1.29-2.73)*	2.16 (0.95-4.87)	1.27 (0.30-5.34)
	Preterm: C	−22.86 (−83.44 to 37.72)	0.83 (0.36-1.89)	0.76 (0.09-5.92)	1.37 (0.29-6.59)
	Multiparous: D	−23.94 (−68.70 to 20.82)	0.69 (0.36-1.31)	1.51 (0.48-4.77)	0.89 (0.10-7.75)
AMTSL	(if Class A)	64.02 (30.16-97.89)***	1.96 (1.41-2.72)*	2.74 (1.36-5.52)*	2.05 (0.67-6.31)
Interaction	Physiologic: A	Reference	Reference	Reference	Reference
	Dysfunctional: B	−17.45 (−73.92 to 39.02)	0.61 (0.38-0.98)*	0.54 (0.21-1.43)	1.58 (0.29-8.36)
	Preterm: C	−3.78 (−92.72 to 85.17)	0.83 (0.29-2.31)	1.15 (0.11-11.71)	Dropped collinearity
	Multiparous: D	3.59 (−61.49 to 68.77)	1.31 (0.61-2.78)	0.78 (0.20-2.99)	1.26 (0.11-14.91)

^*P < 0.05,

^**P < 0.01,

^***P < 0.001.

OR, odds ratio.