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. 2021 Jun 8;7(7):e707. doi: 10.1097/TXD.0000000000001154

TABLE 3.

Multivariate Cox proportional hazards regression of associationsa with graft failure in liver transplant recipients in the pre-DAA (2008–2012) and DAA (2014–2019) eras

Pre-DAA era (ref. HIV/HCV) HR (95% CI) P DAA era (ref. HIV/HCV) HR (95% CI) P
HIV+/HCV+ 1.85 (1.31-2.59) <0.001 HIV+/HCV+ 1.24 (0.81-1.89) 0.308
HIV+/HCV 1.21 (0.77-1.91) 0.840 HIV+/HCV 1.23 (0.81-1.88) 0.324
HIV/HCV+ 1.24 (1.19-1.29) <0.001 HIV/HCV+ 1.01 (0.96-1.07) 0.709

aAdjusted for donor and recipient age and DCD graft use.

CI, confidence interval; DAA, direct-acting antiviral; DCD, donation after circulatory death; HCV, hepatitis C virus.