Table 1.
Demographics, clinical characteristics, and hospital management of maternal-infant dyads affected by perinatal SARS-CoV-2 infection (n=70)
| N (%) | |
|---|---|
| Demographic Characteristics | |
| Maternal age | |
| <20 years | 2 (3%) |
| 20 to <30 years | 31 (44%) |
| 30 to <40 years | 31 (44%) |
| >40 years | 6 (9%) |
| Maternal race/ethnicity | |
| Asian | 3 (4%) |
| Black or African American | 14 (20%) |
| Latinx | 32 (46%) |
| White | 13 (19%) |
| Other/multi-ethnic | 1 (1%) |
| Missing/unknown | 7 (10%) |
| Infant sex | |
| Female | 35 (50%) |
| Male | 35 (50%) |
| United States region | |
| Northeast | 39 (56%) |
| Midwest | 7 (10%) |
| South | 10 (14%) |
| West | 14 (20%) |
| Delivery and Birth Characteristics | |
| Mode of delivery | |
| Vaginal | 45 (64 %) |
| Cesarean | 25 (36%) |
| Length of gestation | |
| 35 to <37 weeks | 4 (6%) |
| 37 to <38 weeks | 14 (20%) |
| 38 to <39 weeks | 10 (14%) |
| 39 to <40 weeks | 21 (30%) |
| ≥40 weeks | 21 (30%) |
| Birthweight | |
| Appropriate for gestational age | 59 (84%) |
| Small for gestational age | 7 (10%) |
| Large for gestational age | 4 (6%) |
| Delivery room resuscitation | |
| Routine warm, dry, stimulation and suction | 63 (90%) |
| Positive pressure ventilation (PPV) | 3 (4%) |
| Continuous positive airway pressure (CPAP) | 3 (4%) |
| Cardiopulmonary resuscitation and intubation | 1 (1%) |
| SARS-CoV-2 | |
| Maternal SARS-CoV-2 diagnosis, days before delivery (range, mean [SD])* | 2–29, 7.1 [7.9] |
| Maternal SARS-CoV-2 symptoms | |
| Maternal symptoms at any point | 42 (63%) |
| Maternal symptoms at time of delivery | 25 (36%) |
| Maternal symptoms unknown | 3 (4%) |
| Neonate tested for SARS-CoV-2 by upper respiratory swab RT-PCR | 57 (81%) |
| Hours of life at swab #1 (range, mean [SD]) | 2–120, 30 [16.0] |
| Hours of life at swab #2 (range, mean [SD]) | 36–384, 88 [101.0] |
| SARS-CoV-2 Related Clinical Management | |
| Pediatric provider attended delivery | 50 (72%) |
| Pediatric provider attended due to maternal SARS-CoV-2 | 24 (34%) |
| Service to which infant was admitted | |
| Well-baby nursery | 65 (93%) |
| Pediatric hospitalist/ward (with separation) | 1 (2%) |
| Intensive care nursery (with separation) | 4 (6%) |
| Co-location of mother and infant | 34 (49%) |
| Length of stay (range, mean [SD]) | 1– 4, 1.9 [1.8] |
| Discharge to which caregiver(s) | |
| Parents | 65 (93%) |
| Other healthy caregiver | 5 (7%) |
| Timing of post-discharge follow-up (range, mean [SD]) | 1–4, 1.7 [0.9] |
| Method of post-discharge follow-up | |
| In person clinic appointment | 52 (74%) |
| Tele-health appointment | 18 (26%) |
RT-PCR: reverse transcription polymerase chain reaction, SARS-CoV-2: severe acute respiratory syndrome coronavirus 2, SD: standard deviation;
*
diagnosis timing per collection date of the first respiratory swab that was positive for SARS-CoV-2 (all by RT-PCR)