Table II: Source-specific protein lists for ECM derived from the three cell types.
Proteins presented here were identified in the ECM of one cell-type and not detected in the others. For Bm ECM proteins, only proteins present in at least 5 donors were considered (or in at least 3 donors for the secreted factors).
| Ad ECM | ||
|---|---|---|
| Gene Symbol | Protein | |
| Collagens | COL15A1 | Collagen XV α1 |
| Glycoproteins | FGL2 | Fibrinogen-like 2 |
| TNXB | Tenascin XB | |
| Regulators | ITIH3 | Inter-alpha (globulin) inhibitor H3 |
| SERPINA5 | Serpin peptidase inhibitor, clade A, member 5 | |
| Secreted factors | SCUBE3 | Signal peptide, CUB domain, EGF-like 3 |
| CTGF | Connective tissue growth factor | |
| Der ECM | ||
| Glycoproteins | LTBP4 | Latent transforming growth factor beta binding protein 4 |
| MATN2 | Matrillin 2 | |
| THBS3 | Thrombospondin 3 | |
| THSD4 | Thrombospondin, type 1 domain containing 4 | |
| Regulators | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADAMTSL4 | ADAMTS-like 4 | |
| CD109 | CD109 molecule | |
| P4HA1 | Prolyl 4-hydroxylase, alpha polypeptide I | |
| PRSS12 | Neurotrypsin | |
| SERPINC1 | Serpin peptidase inhibitor, clade C, member 1 | |
| Secreted factors | MDK | Midkine |
| SFRP1 | Secreted frizzled-related protein 1 | |
| WNT5A | Wingless-type MMTV integration site family, member 5A | |
| Bm ECM | ||
| Glycoproteins | AEBP1 | AE-bindin prot. 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | |
| EFEMP2 | Fibulin 3 | |
| FGB | Fibrinogen β | |
| FGG | Fibrinogen γ | |
| MFGE8 | Milk fat globule-EGF factor 8 protein | |
| VWA1 | Von Willebrand factor A domain containing prot. 1 | |
| Collagens | COL14A1 | Collagen XIV α1 |
| Regulators | CTSB | Cathepsin B |
| LOXL1 | Lysyl oxidase-like 1 | |
| MMP2 | Matrix metallopeptidase 2 | |
| ECM-affiliated proteins | ANXA5 | Annexin A5 |
| LGALS3 | Lectin galactoside-binding soluble 3 | |
| Secreted factors | S100A6/10 | S100 calcium binding protein A6/10 |