Figure 3.

Rates of URA3-GC mutations and rates of deletions (≥ 5 bp) and QP mutations in various genetic backgrounds. Error bars indicate 95% confidence limits. Numbers in parentheses show whether the rates were determined in 23°C or 30°C cultures. WT indicates the wild-type strain. (A) Rates of URA3-GC mutations. (B) Rates of deletions and QP (ura3-GC-366TC) mutations. As shown in Supplementary Figure S4, the QP mutation is likely the consequence of template switching between two inverted repeats, resulting in formation of a perfect palindrome from a quasi-palindrome. Rates of other types of mutations in each strain are shown in Supplementary Table S3. Asterisks indicate that no events were observed for that class of mutation.