Table 1. Comparison of patient characteristics between the good and the poor adherence groups.
| Patient characteristics | Good adherence (n = 893) | Poor adherence (n = 164) | p value |
|---|---|---|---|
| Female | 356 (40) | 60 (37) | 0.438 |
| Age (years) | 70 [21–94] | 74 [22–89] | <0.001 |
| Body weight (kg) | 61 [32.3–133] | 59 [25.7–146] | 0.124 |
| BMI | 23.5 [13.8–47.4] | 23.1 [16.1–58.1] | 0.529 |
| Tobacco use | 406 (45) | 84 (51) | 0.175 |
| Alcohol use | 376 (42) | 53 (32) | 0.020 |
| Diabetes mellitus | 166 (19) | 37 (23) | 0.069 |
| Heart failure | 36 (4) | 12 (7) | 0.053 |
| Baseline biological parameters | |||
| AST (U/L) | 26 [7–1247] | 26 [8–231] | 0.595 |
| ALT (U/L) | 22 [3–563] | 21 [5–335] | 0.300 |
| γ-GTP (U/L) | 32 [2–1127] | 32 [2–927] | 0.764 |
| T-Bil (mg/dL) | 0.8 [0.2–29] | 0.7 [0.3–2.7] | 0.066 |
| BUN (mg/dL) | 17.8 [5.2–97.7] | 21.6 [5.0–93.9] | <0.001 |
| eGFR (mL/min) | 63 [3–124] | 51 [3–128] | <0.001 |
| Systolic blood pressure (mmHg) | 131 [50–197] | 141 [82–197] | <0.001 |
| Diastolic blood pressure (mmHg) | 73 [35–124] | 75 [45–115] | 0.035 |
Values are presented as median [range] or number (%).
Fisher’s exact test or Mann-Whitney U test was performed. ALT: alanine transaminase; AST: aspartate transaminase; BMI: body mass index; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; γ-GTP: gamma-glutamyl transpeptidase; T-Bil: total bilirubin