Figure 5.

Sepsis accentuates the effect of extreme prematurity on the NK cell compartment. (a–c) show the proportions of total NK, CD56^dim‐cell and CD56^bright NK‐cell frequencies, respectively, in 14‐day‐old ELGAN/ELBW with sepsis onset within 14 days of life, after day 14 of age, or no sepsis. (d–f) show the proportions of total NK, CD56^dim‐cell and CD56^bright NK cell frequencies, respectively, in 28‐day‐old ELGAN/ELBW with sepsis onset within 28 days after birth or no sepsis. The proportions of total NK, CD56^dim and CD56^bright NK cells in paired samples from day 14 and week 36 are shown for cases with (g–i) or without (j–l) sepsis. Box and whisker plots show median as the central line and error bars represent minimum to maximum. The Mann–Whitney U‐test was used for group comparisons, and the Wilcoxon signed‐rank test was used to assess differences between pairs.