Table 2.
Blood glucose endpoints: 20 g crystal lactulose vs water
|
20 g crystal lactulose
|
Water
|
Treatment
|
P
value
|
|||
|
Variable
|
n
|
LS mean (95%CI)
|
n
|
LS mean (95%CI)
|
Difference (95%CI)
|
|
| AUCbaseline_c (0-180 min) (min/mmol/L) | 16 | -54.40 (-100.23, -8.57) | 16 | -53.21 (-99.14, -7.28) | -1.20 (-60.78, 58.39) | 0.9682 |
| AUC(0-180 min) (min/mmol/L) | 16 | 1218.33 (1172.50, 1264.16) | 16 | 1219.53 (1173.60, 1265.46) | -1.20 (-60.78, 58.39) | 0.9682 |
| iAUC(0-180 min) (min/mmol/L) | 16 | 17.00 (-14.43, 48.43) | 16 | 18.44 (-13.04, 49.92) | -1.44 (-45.16, 42.29) | 0.9478 |
| Cmax (mmol/L) | 16 | 7.50 (7.17, 7.82) | 16 | 7.44 (7.11, 7.77) | 0.06 (-0.38, 0.50) | 0.7999 |
| Max_increase (mmol/L) | 16 | 0.43 (0.10, 0.75) | 16 | 0.37 (0.04, 0.70) | 0.06 (-0.38, 0.50) | 0.7999 |
AUCbaseline_c (0-180 min): Baseline-corrected area under the curve from 0 to 180 min; AUC(0-180 min): Area under the curve from 0 to 180 min; iAUC(0-180 min): Incremental AUC(0-180 min), i.e., area above baseline levels of blood glucose concentration; Cmax: Maximum blood glucose concentration; Max_increase: Maximum blood glucose concentration minus baseline value; LS mean: Adjusted least square mean obtained from analysis of covariance model.