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. 2021 Jan 27;32(7):1249–1275. doi: 10.1007/s00198-020-05742-0

Table 3.

Recommendations for timing of bone densitometry in follow-up

Guideline Mode First test (if stated separately) Intervals for repeat tests (if stated)
Australia DXA

≥ 2 years when considering efficacy of treatment, risk assessment or decision to change or interrupt treatment

Every 1 year in patients at high risk

China (Orthopedic) DXA 1 year after starting treatment
China (CSOBMR) Unspecified (bone density measurement) 1 year after starting or changing treatment Every 1–2 years when effect has stabilized
China (Geriatrics) DXA or QCT (if available)

Unspecified

(Monitor efficacy)

Biochemical markers of bone turnover Every 3–6 months
Chinese Taipei DXA

2 years after starting treatment

< 2 years after starting treatment in patients with glucocorticoid-induced osteoporosis

Hong Kong SAR BMD (not specified)

1–2 years after starting treatment in patients treated with antiresorptive treatment

1 year after starting treatment in patients treated with bone-forming agents

2–3 after therapeutic effect established
India (IMS) DXA (use same DXA machine) 2 years
India (ISBMR) DXA (if available) 2 years
Indonesia BMD (not specified) 1–2 to evaluate treatment response (defined as stable over 1 year)
Japan BMD (not specified) 1 year after starting treatment > 1 year (unspecified)—after 1 year’s treatment with bisphosphonates, intervals longer than 1 year needed to see change in BMD
Malaysia DXA Not specified

Not specified

(Monitoring the effect of therapy)

New Zealand BMD (not specified) 4–5 years after starting treatment to determine whether bisphosphonates treatment should continue ≥ 3 years (intervals < 3 years not recommended in most patients)
Singapore DXA 1–2 years after starting treatment to establish clinical effectiveness Every 2–3 years after clinical effectiveness established
South Korea DXA

Every 1 year until normal BMD (T-score > − 1.0)

2 years after previous normal BMD

Thailand DXA (Use same axial DXA analyzer) > 1 year
Vietnam Not specified 1–2 years 1–2 years

BMD bone mineral density, DXA dual-energy X-ray absorptiometry, QCT quantitative computed tomography