Table 2.
Natural history of AKI in Renal Transplantation
| Whole AKI cohort | CA-AKI | HA-AKI | p value CA vs. HA-AKI | |
|---|---|---|---|---|
| Number of AKI episodes, n (% of whole cohort) | 937 | 538 (57.4) | 273 (29.1) | |
| Mean age at time of AKI ± SD (years) | 55.2 ± 14.7 | 53.2 ± 14.6 | 59.6 ± 13.2 | p < 0.001 |
| AKI stage 1, % (n) | 64.7 (606) | 64.5 (312) | 78.4 (214) | p < 0.001 |
| AKI stage 2, % (n) | 7.3 (68) | 7.8 (42) | 6.6 (18) | p = n/s |
| AKI stage 3, % (n) | 28.0 (263) | 34.2 (184) | 18.4 (41) | p < 0.001 |
| Outcome measures | ||||
| 30-day mortality, % (n) | 19.8 (87) | 4.8 (26) | 16.8 (46) | p < 0.001 |
| Overall mortality, % (n) | 34.8 (153) | |||
| 30-day recovery of renal function, % (n) | 75 (615) | 70.2 (340)^ | 81.8 (185) | p < 0.001 |
| Process measures | ||||
| Repeat test within 30 days, % (n) | 96.1 (900) | 93.9 (505) | 98.8 (270) | p = 0.001 |
| Mean time to repeat ± SD (days) | 3.8 ± 5.9 | 5.5 ± 7.13 | 1.43 ± 1.87 | p < 0.001 |
Recovery of renal function included only surviving patients with available tests of follow-up renal function: 710 episodes were included in the 30-day recovery of renal function analysis (484 episodes, CA; 226 episodes, HA-AKI)