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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Am J Surg Pathol. 2021 Jul 1;45(7):951–961. doi: 10.1097/PAS.0000000000001685

Table 2:

Multivariable survival analysis: p16/HPV test combination groups.

Disease Free Survival HRR* 95% CI Significance (P)
Double Positive (Reference category) 1.00
Discordant 1.91 0.93 – 3.95 0.08
Double Negative 3.64 2.40 – 5.53 <0.001
Age (HRR associated with an additional year of life) 1.03 1.01 – 1.05 0.004
Former or Current Smoker 2.28 1.40 – 3.73 0.001
T3/T4 1.56 1.05 – 2.33 0.03
Definitive / Chemo only 1.46 0.97 – 2.15 0.07
Overall Survival HRR* 95% CI Significance (P)
Double Positive (Reference category) 1.00
Discordant 1.91 0.91 – 3.99 0.09
Double Negative 4.13 2.67 – 6.37 <0.001
Age (HRR associated with an additional year of life) 1.03 1.01 – 1.05 0.01
Former or Current Smoker 2.11 1.27 – 3.50 0.004
T3/T4 1.69 1.11 – 2.56 0.01
Definitive / Chemo Only 1.65 1.09 – 2.49 0.02
Double Positive (Reference category) 1.91 0.91 – 3.99 0.09
*

Hazard Rate Ratio