Table 1.

A schematic overview of animal characteristics in the infarct size study (I) at the stages prediabetes (6 weeks), onset diabetes (12 weeks) and mature diabetes (24 weeks)

Type	Non-diabetic			Prediabetes
Group	Con (n = 8)	DiMal 0.1 mM (n = 7)	DiMal 0.6 mM (n = 7)	Con (n = 8)	DiMal 0.1 mM (n = 8)	DiMal 0.6 mM (n = 7)
6 weeks
Bodyweight (BW), g	158 ± 8	173 ± 5	152 ± 3	220 ± 7*	199 ± 6	213 ± 11
Heartweight (HW), g	0.60 ± 0.02	0.66 ± 0.03	0.62 ± 0.02	0.82 ± 0.04*	0.67 ± 0.02*	0.77 ± 0.03
HW/BW ratio	0.38 ± 0.005	0.38 ± 0.01	0.41 ± 0.01	0.37 ± 0.02	0.33 ± 0.008	0.36 ± 0.005
B-glucose, mmol/L	3.4 ± 0.1	4.5 ± 0.2*	3.4 ± 0.1	5.4 ± 0.2*	5.7 ± 0.2	5.1 ± 0.1

Type	Non-diabetic			Onset diabetes
Group	Con (n = 7)	DiMal 0.1 mM (n = 8)	DiMal 0.6 mM (n = 7)	Con (n = 7)	DiMal 0.1 mM (n = 8)	DiMal 0.6 mM (n = 7)
12 weeks
Bodyweight (BW), g	319 ± 10	304 ± 13	306 ± 17	394 ± 15*	388 ± 17	410 ± 13
Heartweight (HW), g	1.0 ± 0.03	0.99 ± 0.02	0.98 ± 0.04	1.2 ± 0.03	1.0 ± 0.07	1.2 ± 0.03
HW/BW ratio	0.31 ± 0.005	0.33 ± 0.01	0.32 ± 0.009	0.30 ± 0.007	0.28 ± 0.02	0.30 ± 0.01
B-glucose, mmol/L	4.0 ± 0.1	5.0 ± 0.2	4.0 ± 0.1	9.9 ± 2*	9.0 ± 1	11 ± 1

Type	Non-diabetic			Mature diabetes
Group	Con (n = 8)	DiMal 0.1 mM (n = 8)	DiMal 0.6 mM (n = 8)	Con (n = 9)	DiMal 0.1 mM (n = 8)	DiMal 0.6 mM (n = 8)
24 weeks
Bodyweight (BW), g	402 ± 8	405 ± 11	407 ± 9	403 ± 12	395 ± 19	387 ± 7
Heartweight (HW), g	1.2 ± 0.05	1.2 ± 0.03	1.2 ± 0.05	1.2 ± 0.04	1.2 ± 0.02	1.2 ± 0.03
HW/BW ratio	0.29 ± 0.01	0.30 ± 0.009	0.29 ± 0.01	0.31 ± 0.008	0.30 ± 0.02	0.30 ± 0.01
B-glucose, mmol/L	4.7 ± 0.2	5.5 ± 0.2	4.6 ± 0.1	15 ± 1*	25 ± 0.7*	13 ± 1

*p < 0.05 compared to control. Results are mean ± SEM