Table 2: Heritability of Network Connectome Structure in the LTS dataset.

Twins’ correlations and ACE structural equation model estimates are displayed. For correlation analyses, heritability is suggested when the correlation between MZ twins is greater than the correlation between DZ twins. ACE variances were unbounded so could be negative. The upper and lower bound of the likelihood-based 95% confidence intervals are displayed inside the squared brackets for the A, C and E parameters. AIC = Akaike’s information criterion, a measure of model fit; lower AIC values indicate better fit, marked in bold in the table.

Measure	Twins’ Correlations			ACE Structural Model
	rmz	rdz	Diff	Model	A [A−,A+]	C [C−,C+]	E [E−,E+]	AIC
Characteristic path length	0.121	0.083	0.04	ACE	0.08[−0.5,0.67]	0.04[−0.43,0.49]	0.87[0.68,1.08]	689.168
				AE	0.13[−0.05,0.31]	NA	0.87[0.69,1.05]	687.197
				CE	NA	0.1[−0.04,0.25]	0.9[0.75,1.04]	687.247
				E	NA	NA	1	687.134
Clustering Coefficient	0.076	0.032	0.04	ACE	0.09[−0.49,0.67]	−0.01[−0.47,0.44]	0.92[0.73,1.13]	449.035
				AE	0.07[−0.11,0.25]	NA	0.93[0.75,1.11]	447.039
				CE	NA	0.05[−0.09,0.2]	0.95[0.8,1.09]	447.128
				E	NA	NA	1	445.635
Global efficiency	−0.003	0.005	−0.01	ACE	−0.02[−0.61,0.58]	0.01[−0.44,0.47]	1[0.79,1.22]	361.762
				AE	0[−0.19,0.19]	NA	1[0.81,1.19]	359.765
				CE	NA	0[−0.15,0.15]	1[0.85,1.15]	359.765
				E	NA	NA	1	357.766
Local efficiency	0.218	0.114	0.1	ACE	0.17[−0.39,0.74]	0.04[−0.44,0.48]	0.79[0.62,0.98]	591.985
				AE	0.21[0.04,0.37]	NA	0.79[0.63,0.96]	590.008
				CE	NA	0.17[0.03,0.3]	0.83[0.7,0.97]	590.337
				E	NA	NA	1	593.680
Modularity	−0.047	0.155	−0.2	ACE	−0.35[−0.92,0.24]	0.31[−0.12,0.73]	1.03[0.81,1.25]	464.684
				AE	0.05[−0.14,0.24]	NA	0.95[0.76,1.14]	464.719
				CE	NA	0.07[−0.07,0.21]	0.93[0.79,1.07]	464.038
				E	NA	NA	1	463.036
Small Worldness	0.138	−0.126	0.26	ACE	0.43[−0.16,1]	−0.32[−0.75,0.13]	0.89[0.69,1.11]	469.122
				AE	0.04[−0.15,0.22]	NA	0.96[0.78,1.15]	469.028
				CE	NA	−0.01[−0.15,0.14]	1.01[0.86,1.15]	469.167
				E	NA	NA	1	467.174