Fig. 2.

High expression of SCHLAP1 is associated with shorter time to BCR, and concepts of inter- and intrafocal heterogeneity in prostate cancer. (A) Kaplan-Meier plot showing the percentage of patients without BCR, stratified by high and low expression of SCHLAP1. (B-C) Percent of patients without BCR, stratified by (B) grade group and expression of SCHLAP1, or (C) stratified by pT stage and expression of SCHLAP1. (D) Interfocal heterogeneity, where SCHLAP1 status varies between tissue samples collected from two different tumor foci. (E) Intrafocal heterogeneity, where the SCHLAP1 status of samples collected from the same focus varies. The outline of each tumor focus is marked with a black line, and the SCHLAP1 status of a sample is indicated by red (high) or blue (low) circles. BCR, biochemical recurrence; GG, grade group; pT, pathological tumor stage.