Table 1.
Baseline descriptive statistics for the full sample and by dementia outcome at follow-up.
| Total | Not impaired | All-cause dementia | Alzheimer’s disease | Vascular dementia | Frontotemporal dementia | |
|---|---|---|---|---|---|---|
| N | 401,422 | 399,624 | 1,798 | 675 | 376 | 81 |
| Neuroticism | 4.12 (3.27) | 4.12 (3.27) | 4.31 (3.41) | 4.11 (3.37) | 4.26 (3.42) | 3.70 (3.45) |
| Age, years | 56.41 (8.07) | 56.38 (8.06) | 64.04 (5.09) | 64.53 (4.38) | 64.59 (4.36) | 61.99 (5.63) |
| Follow-up, years | 8.88 (1.23) | 8.90 (1.21) | 5.95 (2.10) | 6.19 (1.89) | 5.78 (2.14) | 5.49 (2.12) |
| Sex (Women) | 215,518 (53.7%) | 214,733 (53.7%) | 785 (43.7%) | 318 (47.1%) | 138 (36.7%) | 36 (44.4%) |
| College | 133,363 (33.2%) | 133,013 (33.3%) | 350 (19.5%) | 131 (19.4%) | 58 (15.4%) | 27 (33.3%) |
| Deprivation | −1.39 (3.04) | −1.39 (3.03) | −0.86 (3.37) | −1.14 (3.23) | −0.55 (3.47) | −1.53 (3.16) |
| Income | 2.66 (1.20) | 2.66 (1.20) | 1.87 (1.00) | 1.88 (0.96) | 1.72 (0.96) | 2.08 (1.06) |
| Diabetes | 20,418 (5.1%) | 20,154 (5.0%) | 264 (14.7%) | 83 (12.3%) | 94 (25.0%) | 9 (11.1%) |
| Hypertension | 96,621 (24.1%) | 96,071 (24.0%) | 550 (30.6%) | 198 (29.3%) | 127 (33.8%) | 22 (27.2%) |
| Stroke | 4,937 (1.2%) | 4,854 (1.2%) | 83 (4.6%) | 18 (2.7%) | 34 (9.0%) | 2 (2.5%) |
| Heart attack | 9,934 (2.3%) | 9,174 (2.3%) | 160 (8.9%) | 55 (8.1%) | 58 (15.4%) | 7 (8.6%) |
| Obesity | 97,319 (24.2%) | 96,834 (24.2%) | 485 (27.0%) | 163 (24.1%) | 134 (35.6%) | 21 (25.9%) |
| HbA1c, mmol/mol | 36.03 (6.69) | 36.02 (6.67) | 38.88 (9.78) | 38.48 (9.95) | 41.41 (11.16) | 37.18 (9.42) |
| CRP, mg/L | 2.57 (4.32) | 2.57 (4.32) | 3.02 (5.24) | 2.6825 (4.90) | 3.3631 (5.11) | 3.1368 (4.53) |
| LDL, mmol/L | 3.56 (0.87) | 3.56 (0.87) | 3.37 (0.96) | 3.3902 (0.95) | 3.2138 (1.01) | 3.4556 (0.80) |
| Ever smoker | 181,675 (45.3%) | 180,686 (45.2%) | 989 (55.0%) | 346 (51.3%) | 231 (61.4%) | 44 (54.3%) |
| Physical activity | 127.80 (101.73) | 127.83 (101.72) | 120.36 (104.71) | 129.42 (106.83) | 111.80 (103.92) | 116.77 (100.55) |
Notes. Sample size as indicated in the Table except for Income (n = 348,523), physical activity (n = 335,202), HbA1c (n = 373,318), CRP (n = 375,036), and LDL (n = 375,112). Income is the household average total income before tax on a scale from 1 to 5. Physical activity is the sum of minutes performing walking, moderate and vigorous activity.