Table 1. Characteristics of the study population.
Mean (SD) reported for parametric data. Median [IQR] reported for non-parametric data.
| Characteristic | Mean (SD) or Median [IQR] |
|---|---|
| Age – yrs | 53 (11) |
| Male sex - % | 64% |
| Race/Ethnicity | |
| White | 50% |
| Black | 19% |
| Asian | 6% |
| Other/Unknown | 25% |
| BMI – kg/m2 | 31 (6) |
| Systolic blood pressure – mmHg | 149 (21) |
| Diastolic blood pressure – mmHg | 87 (13) |
| Number of antihypertensive medications | 3 (1) |
| Potassium at diagnosis – mEq/L | 3.4 (0.5) |
| Potassium < 3.5 mEq/L at diagnosis | 58% |
| Potassium at AVS – mEq/L | 3.9 (0.7) |
| Plasma aldosterone concentration – ng/dL | 22.8 [16.7–34.0] |
| Plasma renin activity – ng/mL/h | 0.5 [0.2–0.6] |
| Aldosterone to renin ratio – (ng/dL)/(ng/mL/h) | 70 [35–160] |
| Cross-sectional imaging findings | |
| Normal adrenal glands | 16% |
| Unilateral adrenal nodule | 76% |
| Bilateral adrenal nodules | 8% |
| Unstimulated LI ≥ 2 - % | 82% |
| Unstimulated LI ≥ 4 - % | 66% |
| Stimulated LI ≥ 4 - % | 61% |
| Unilateral intervention - % | 69% |
| Complete or partial clinical success after unilateral intervention | 83% (64% partial, 19% complete) |
| Complete or partial biochemical success after unilateral intervention | 93% (6% partial, 87% complete) |