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. 2021 Jun 10;12:3541. doi: 10.1038/s41467-021-23913-3

Table 1.

Corresponding relationship between new annotation classification and TBS classification.

New annotation classification Corresponding TBS classification Category Definition
AGC_A (C1) AGC_NOS, AGC_FN, AIS, ADC Glandular intraepithelial lesions Atypical glandular cells, pathological morphology similar to cervical gland cells
AGC_B (C2) AGC_NOS, AGC_FN, AIS, ADC Glandular intraepithelial lesions Atypical glandular cells, other pathological morphology
ASC_L_S (C3) ASCUS, LSIL, ASCH, HSIL, SCC Squamous intraepithelial lesion Single atypical squamous cell with low nuclear/cytoplasmic ratio (excluding Koilocytes)
KC (C4) LSIL Squamous intraepithelial lesion Single koilocyte
ASC_L_F (C5) ASCUS, LSIL, ASCH, HSIL, SCC Squamous intraepithelial lesion Atypical squamous cells with low nuclear/cytoplasmic ratio, arranged in sheets or clusters
ASC_H_B (C6) ASCUS, ASCH, HSIL, SCC Squamous intraepithelial lesion Atypical squamous cells with high nuclear/cytoplasmic ratio, arranged in clusters (cells number ≥ 10)
ASC_H_M (C7) ASCUS, ASCH, HSIL, SCC Squamous intraepithelial lesion Atypical squamous cells with high nuclear/cytoplasmic ratio, arranged in clusters (2 ≤ cells number ≤ 10)
ASC_H_S (C8) ASCUS, ASCH, HSIL, SCC Squamous intraepithelial lesion Single atypical squamous cell with high nuclear/cytoplasmic ratio
SCC_R (C9) SCC Squamous intraepithelial lesion Keratinizing squamous cell carcinoma cells
SCC_G (C10) SCC Squamous intraepithelial lesion Non-Keratinizing squamous carcinoma cells
MC (C11) NIL Normal Superficial squamous epithelium
SC (C12) NIL Normal Single normal cell with high nuclear/cytoplasmic ratio (Including parabasal cells, lymphocyte cells, and reserve cells etc.)
RC (C13) NIL Normal Repair and metaplasia cells
GEC (C14) NIL Normal Glandular epithelial cells of cervical tube
EMC (C15) EMC EMC Endometrial cells
TRI (C16) TRI Infectious lesion Trichomonas vaginalis
CAN (C17) CAN Infectious lesion Candida albicans
HSV (C18) HSV Infectious lesion Herpes simplex virus
ACTINO (C19) ACTINO Infectious lesion Actinomycetes
CC (C20) CC Infectious lesion Clue cells
PH (C21) NIL Evidence of infectious lesion Perinuclear halo
Neutrophils (C22) NIL Normal Neutrophils
Mucus (C23) NIL Normal Mucus
Debris (C24) NIL Normal Debris