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. 2021 May 28;12:623192. doi: 10.3389/fpsyt.2021.623192

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Copyright © 2021 Reponen, Tesli, Dieset, Steen, Vedal, Szabo, Werner, Lunding, Johansen, Rødevand, Andreassen and Ueland.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Leptin, adiponectin and their ratio (L/A) in severe mental illness (SMI) and according to antipsychotic (AP) treatment. To the left: multivariate analysis of covariance with dependent variable: leptin (A), adiponectin (B) or L/A (C), with adjustment for age, sex, duration of illness, mood stabilizers (DDD), duration of AP treatment and additional adjustment with body mass index (BMI). *p < 0.05 **p < 0.01 ***p < 0.001 vs. healthy controls; ^†p < 0.05, ^††p < 0.01, ^†††p < 0.001 vs. AP-. To the right: correlation between log-transferred leptin, adiponectin or L/A, and BMI. Numbers indicate the regression coefficient. ***p < 0.001.