Table 2.
Years (y) recruited | <1982 | 1980–1985 | 2002–2003 | 2000–2006 | 1995–2010 | 1989–2012 | 2008–2015 | 2015–2016 |
---|---|---|---|---|---|---|---|---|
Country | Canada | Mexico | Germany | Italy | Taiwan | USA | France | India |
Cohort size | 39 | 110 | 118 | 59 | 195 | 234 | 114 | 55 |
Y f/u | 1.9 | 12.2 | 4 | 3 | >1.5 | –b | 2.5 | <5 |
SpA # (%) | All SEA | 35(32) JoAS | All SpA mNY or ESSG | All ERA | 73(37) ERA | All ERA | All SpA | All ERA |
Peripheral arthritis | ||||||||
% Knee | 83 | 100 | 77 | 65 | 52 | 46 | 58 | – |
% Ankle | – | 80 | 40 | 48 | 38 | 36 | 38 | 27 |
% Hip | – | 83 | 38 | – | 43 | 19 | 46 | – |
% Mid-foot | – | 89 | 9.3 | 58 | – | – | 9 | 36 by ultrasound 54 by MRI |
% Fingers | – | 23 | 25 | – | 18a | – | 12 | – |
% Toes or MTP | – | 86 | 27 | – | 16a | – | 17 | 4 toes 16 MTP |
% Wrist | – | 14 | – | – | 16 | 20 | 25 | – |
% Dactylitis | – | – | 13 | – | – | – | 13 | 7.3 (toes) |
Enthesitis | – | – | ||||||
% Achilles | 51 | 34 | 28 | 33 | 74c | 44 | ||
% Plantar front insertion | – | – | – | – | 39 | 20d See note | ||
% Plantar calcaneal insertion | 67 | 54 | 38 | – | See notec | See noted | ||
% Knee | 49 | 23 | – | 44 | 46 | – | ||
% Pelvis | 5 | 9 | – | 30 | 22c | – | ||
% Greater trochanter | – | 14 | – | – | See Notec | – | ||
References | (18) | (39) | (17) | (24) | (25) | (26) | (16) | (40) |
Cohorts are listed across the top by years of recruitment and nationality. ERA, enthesitis related arthritis; ESSG, European Spondyloarthropathy Study Group; mNY, modified New York criteria for ankylosing spondylitis (28). ASAS, Assessment of Spondyloarthritis International Society; F/u, median or mean follow up, depending upon the study; MTP, metatarsal-phalangeal joints. No data or insufficient data (<1%) designated as –. Knee includes tibial tuberosity, infrapatellar, and suprapatellar sites. Pelvis includes ischial tuberosity, iliac crest, and interosseous ligaments of sacroiliac joint.
Specified as “small joints” of fingers or feet.
Cross sectional inception cohort without specified follow up.
74% had Achilles or plantar calcaneal insertion enthesitis. “Pelvis” was lumped with greater trochanteric enthesitis in this study.
Not specified if frontal or calcaneal plantar fasciitis.