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. 2021 May 28;8:680916. doi: 10.3389/fmed.2021.680916

Table 2.

Anatomic distribution of peripheral arthritis and enthesitis.

Years (y) recruited <1982 1980–1985 2002–2003 2000–2006 1995–2010 1989–2012 2008–2015 2015–2016
Country Canada Mexico Germany Italy Taiwan USA France India
Cohort size 39 110 118 59 195 234 114 55
Y f/u 1.9 12.2 4 3 >1.5 b 2.5 <5
SpA # (%) All SEA 35(32) JoAS All SpA mNY or ESSG All ERA 73(37) ERA All ERA All SpA All ERA
Peripheral arthritis
% Knee 83 100 77 65 52 46 58
% Ankle 80 40 48 38 36 38 27
% Hip 83 38 43 19 46
% Mid-foot 89 9.3 58 9 36 by ultrasound
54 by MRI
% Fingers 23 25 18a 12
% Toes or MTP 86 27 16a 17 4 toes 16 MTP
% Wrist 14 16 20 25
% Dactylitis 13 13 7.3 (toes)
Enthesitis
% Achilles 51 34 28 33 74c 44
% Plantar front insertion 39 20d See note
% Plantar calcaneal insertion 67 54 38 See notec See noted
% Knee 49 23 44 46
% Pelvis 5 9 30 22c
% Greater trochanter 14 See Notec
References (18) (39) (17) (24) (25) (26) (16) (40)

Cohorts are listed across the top by years of recruitment and nationality. ERA, enthesitis related arthritis; ESSG, European Spondyloarthropathy Study Group; mNY, modified New York criteria for ankylosing spondylitis (28). ASAS, Assessment of Spondyloarthritis International Society; F/u, median or mean follow up, depending upon the study; MTP, metatarsal-phalangeal joints. No data or insufficient data (<1%) designated as –. Knee includes tibial tuberosity, infrapatellar, and suprapatellar sites. Pelvis includes ischial tuberosity, iliac crest, and interosseous ligaments of sacroiliac joint.

a

Specified as “small joints” of fingers or feet.

b

Cross sectional inception cohort without specified follow up.

c

74% had Achilles or plantar calcaneal insertion enthesitis. “Pelvis” was lumped with greater trochanteric enthesitis in this study.

d

Not specified if frontal or calcaneal plantar fasciitis.