Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 10;12:3539. doi: 10.1038/s41467-021-23906-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a Left: relationship between NAc firing rates in familiar environment and restraint, with line of equality for reference. Right: summary of data from left panel. Restraint inhibited overall NAc neuron firing rate (***P < 0.0001 two-tailed signed-rank tests, n = 81 neurons). Data are mean ± s.e.m. b Distribution of NAc neurons excited, inhibited, and unmodulated by restraint. c Left: the spike-phase relationship for example restraint-inhibited NAc neuron. The activity was uniformly distributed across 4 Hz filtered NAc LFP phase angles during familiar environment exploration, but phase-locked during restraint. Center: Relationship between the pairwise phase consistency (PPC) of restraint-inhibited NAc neurons during familiar environment exploration and restraint, with line of equality for reference. Right: summary of data from center panel. Restraint-inhibited NAc neurons increased phase-locking to the 4 Hz filtered NAc LFP during restraint (***P < 0.0001, two-tailed signed-rank test, n = 48 neurons). Data are mean ± s.e.m. d Same as c, but with restraint-excited NAc neurons. Restraint-excited NAc neurons did not increase phase locking to the NAc LFP. (P = 0.33, two-tailed signed-rank test, n = 17 neurons). Data are mean ± s.e.m.