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. 2021 Jun 5;397(10290):2182–2193. doi: 10.1016/S0140-6736(21)00731-5

Table 3.

Summary of analyses of relative reduction of ovarian and tubal cancer deaths

Number of women (n) Deaths (n) Maximum χ2 or mortality reduction (hazard ratio) p value
Primary analysis*(ovarian and tubal cancer deaths)
MMS 50 625 296 0·41 0·58
USS 50 622 291 1·23 0·36
No screening 101 314 619 .. ..
Subgroup outcome analysis*(invasive epithelial ovarian and tubal cancer)
MMS 50 625 295 0·41 0·60
USS 50 622 287 1·37 0·33
No screening 101 314 617 .. ..
Secondary analysis(all data 2001–20)
MMS 50 625 296 0·96 (0·83 to 1·10; 0·068) 0·52
USS 50 622 291 0·94 (0·82 to 1·08; 0·067) 0·37
No screening 101 314 619 .. ..
Secondary analysis(only data 2015–20)
MMS 45 999 136 1·05 (0·86 to 1·30; 0·112) 0·63
USS 46 079 128 0·99 (0·80 to 1·22; 0·107) 0·91
No screening 91 808 258 .. ..

Data are maximum χ2 for primary and subgroup analyses or mortality reduction (95% CI; SE) for secondary analyses. MMS=multimodal screening. USS=ultrasound screening.

*

Versatile test.

Cox model.