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. 2021 May 28;13:679688. doi: 10.3389/fnagi.2021.679688

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Copyright © 2021 Yin, Ibrahim, Petersen and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of aging and age-related diseases using autoantibodies against ribosomal proteins. (A) Path plot of sensitivity and specificity for models includes the 2 to 20 top selected autoantibodies against ribosomal proteins for aging and neurodegenerative diseases. (B) Path plot of the accuracy rate of classification and its SD across 500 permutations for models includes the top 2 to 20 selected autoantibodies against ribosomal proteins for aging and neurodegenerative diseases. (C) Heatmap of importance index of top 5 selected autoantibodies against ribosomal proteins in aging and neurodegenerative diseases.