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. 2021 May 28;15:662784. doi: 10.3389/fnins.2021.662784

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Copyright © 2021 Bučková, Kopal, Řasová, Tintěra and Hlinka.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of data. (A) Every subject's data consists of two preprocessed visits providing fMRI time series across all voxels. The time series may be averaged over atlas regions and correlated together to form functional connectivity matrices (see D). (B) Boxplots of quantitative clinical variables—Age, EDSS, Years since diagnosis, and BMI. (C) Distributions of the percentage of outliers, average DVARS and average FD measures across all subjects (visit 1: blue, visit 2: orange). (D) Average of functional connectivity matrices of the first and the second visit of all subjects and a difference of both matrices.